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Virus

Zika virus

Aedes flavivirus, congenital microcephaly

ZEE-kuh VY-rus

flavivirusarbovirusmosquito-borneaedescongenitalrna-virus

High-yield clue

Aedes flavivirus classically linked to congenital microcephaly, and it can also spread sexually and across the placenta.

Overview

A positive-sense single-stranded RNA flavivirus spread mainly by Aedes mosquitoes but also by sexual and vertical (mother-to-fetus) routes, studied for its link to congenital malformations.

Classification

  • Flaviviridae
  • Genus Orthoflavivirus
  • Positive-sense ssRNA
  • Enveloped
  • Arbovirus

Lab & identification clues

  • RNA detection (NAAT) vocabulary
  • Flavivirus serologic cross-reactivity concept
  • Neurotropism study framing

Associations

  • Aedes vector plus sexual and vertical transmission
  • Congenital Zika syndrome and microcephaly vocabulary
  • Guillain-Barre syndrome association
  • Explosive outbreak epidemiology

Commonly confused with

  • Dengue virus
  • Rubella virus

Frequently asked questions

What is Zika virus?

A positive-sense single-stranded RNA flavivirus spread mainly by Aedes mosquitoes but also by sexual and vertical (mother-to-fetus) routes, studied for its link to congenital malformations.

What are the lab clues for Zika virus?

Lab clues for Zika virus include RNA detection (NAAT) vocabulary, Flavivirus serologic cross-reactivity concept, and Neurotropism study framing.

What is Zika virus commonly confused with?

Zika virus is commonly confused with Dengue virus and Rubella virus.

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundations - sourceNCBI Bookshelf: Medical Microbiology organism chapters - sourceCDC: CDC disease and public-health topic pages - source